Title

Myasthenia gravis in a child with sequelae of opsoclonus-myoclonus syndrome

Author

Wilfong AA; Fernandez F

Address

Department of Pediatrics, Baylor College of Medicine, Houston, Texas

Source

Can J Neurol Sci, 19(1):88-9 1992 Feb

Abstract

Immune-mediated myasthenia gravis occurred in a 13-month-old girl who had sequelae of an opsoclonus-myoclonus syndrome. She had an abnormal Raji cell assay along with elevated antiacetylcholine receptor and antithyroglobulin antibodies. No evidence of an associated malignancy was found with either condition. Clearly, the co-occurrence of two diseases within a single patient does not establish a common pathogenesis. Nevertheless, this is a provocative association and may point to an immunologically mediated process in the opsoclonus-myoclonus syndrome.

Language

English

Unique Identifier

92224066

MESH Headings

Case Report ; Female ; Human ; Infant ; Myasthenia Gravis *ET/IM/PP ; Myoclonus *CO/IM ; Ocular Motility Disorders *ET/PP ; Pyridostigmine Bromide TU ; Receptors, Cholinergic IM ; Syndrome

Publication Type

JOURNAL  ARTICLE

ISSN

0317-1671

Country of Publication

CANADA

CAS Registry Number

0 (Receptors, Cholinergic); 101-26-8 (Pyridostigmine Bromide)